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Identification of low molecular weight degradation merchandise from chitin and chitosan
Identification of low molecular weight degradation merchandise from chitin and chitosan by electrospray ionization time-of-flight mass spectrometry
The helpful results offered by chitosan oligosaccharides (COS) make them of curiosity in medical analysis.
The monomers that represent COS confer distinct properties, so controlling COS composition throughout their manufacturing is important.
On this work, we degraded chitin and chitosan polymers and recognized low molecular weight merchandise resembling COS that shaped, utilizing electrospray ionization time-of-flight mass spectrometry.
Our outcomes present that hydrochloric acid, hydrogen peroxide, and nitrous acid generate distinct merchandise from chitin and chitosan.
Hydrochloric acid degrades chitin and chitosan to provide glucosamine (GlcN) monomers and oligomers. Hydrogen peroxide degrades chitosan to provide GlcN and N-acetyl-d-glucosamine (GlcNAc) monomers and oligomers, and nitrous acid degrades chitosan to provide 2,5-anhydro- d-mannose.
Our research present that COS composition is dictated by each the degradation protocol and the beginning polymer. Moreover, our outcomes allow number of degradation protocols primarily based on their capacity to degrade chitin and chitosan and facilitate the manufacturing of COS with desired compositions.
Key phrases: Chitin; Chitosan; Mass spectrometry; Polysaccharide degradation.
Influenza A Virus H3N2 Brisbane 10/07 |
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MBS143232-001mg | MyBiosource | 0.01mg | EUR 240 |
Influenza A Virus H3N2 Brisbane 10/07 |
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MBS143232-005mg | MyBiosource | 0.05mg | EUR 310 |
Influenza A Virus H3N2 Brisbane 10/07 |
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MBS143232-1mg | MyBiosource | 1mg | EUR 2375 |
Influenza A Virus H3N2 Brisbane 10/07 |
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MBS143232-5x1mg | MyBiosource | 5x1mg | EUR 10370 |
H3N2 Influenza-A Virus Brisbane 10/07 |
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rAP-5410 | Angio Proteomie | Inquiry | Ask for price |
Influenza A Virus H3N2 Brisbane 10 / 07 Protein |
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20-abx260509 | Abbexa |
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Influenza A Virus H3N2 Brisbane 10 / 07 Protein |
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abx260509-10g | Abbexa | 10 µg | EUR 325 |
Influenza A Virus H3N2 Brisbane 10 / 07 Protein |
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abx260509-2g | Abbexa | 2 µg | EUR 225 |
Influenza A Strain A/Brisbane/10/07 (H3N2) Antigen |
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11-567 | ProSci | 0.1 mg | EUR 632.4 |
Description: Influenza A (A/Brisbane/10/07), Influenza A Virus, Strain A/Brisbane/10/07 (H3N2) |
Influenza A Strain A/Brisbane/10/07 (H3N2) Protein |
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GWB-T00035 | GenWay Biotech | 1mg | Ask for price |
Influenza A (A/Brisbane/10/06) |
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MBS318591-1mg | MyBiosource | 1mg | EUR 1895 |
Influenza A (A/Brisbane/10/06) |
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MBS318591-5x1mg | MyBiosource | 5x1mg | EUR 8355 |
Influenza A Strain A/Brisbane/10/07 (H3N2) Antigen Liquid |
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IFLUABN1007H3N2ALR100UG | Innovative research | each | EUR 738 |
Description: Influenza A Strain A/Brisbane/10/07 (H3N2) Antigen Liquid |
Influenza A Strain A/Brisbane/10/07 (H3N2) Antigen Liquid |
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Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Insect Cell Lysate (WB positive control) |
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MBS8114355-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Insect Cell Lysate (WB positive control) |
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MBS8114355-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control) |
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MBS8114357-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control) |
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MBS8114357-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
Influenza A, Brisbane 10/06 (H3N2) |
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Influenza A, Brisbane 10/06 (H3N2) |
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Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control) |
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MBS8114356-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control) |
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MBS8114356-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
Influenza A H1N1 (A/Brisbane/02/2018) Neuraminidase/NA Insect Cell Lysate (WB positive control) |
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Influenza A H1N1 (A/Brisbane/02/2018) Nucleoprotein/NP Insect Cell Lysate (WB positive control) |
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Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control) |
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MBS8114342-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control) |
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MBS8114342-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
Influenza B (B/Brisbane/60/2008) Nucleoprotein/NP Insect Cell Lysate (WB positive control) |
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Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA Insect Cell Lysate (WB positive control) |
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MBS8115772-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA Insect Cell Lysate (WB positive control) |
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MBS8115772-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control) |
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MBS8115774-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza B (B/Brisbane/60/2008) Hemagglutinin/HA HEK293 Cell Lysate (WB positive control) |
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MBS8115774-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control) |
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MBS8114341-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza A H1N1 (A/Brisbane/59/2007) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control) |
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MBS8114341-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
Influenza B (B/Brisbane/3/2007) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control) |
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MBS8116043-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza B (B/Brisbane/3/2007) Hemagglutinin/HA1 HEK293 Cell Lysate (WB positive control) |
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MBS8116043-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
H3N2 Influenza A- Virus Brisbane 10/2007 Recombinant |
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rAP-5428 | Angio Proteomie | Inquiry | Ask for price |
Influenza A H3N2 (A/Brisbane/10/2007) HA protein, His Tag |
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E40VAG023 | EnoGene | 20ug | EUR 495 |
Influenza B (B/Brisbane/60/2008) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control) |
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MBS8115773-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza B (B/Brisbane/60/2008) Hemagglutinin (HA1 Subunit) HEK293 Cell Lysate (WB positive control) |
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MBS8115773-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
Influenza A virus H3N2 (Brisbane) Antigen |
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VAC-0271 | Creative BioMart | 0.5ml | EUR 1598.4 |
Description: Protein |
Influenza virus B (B/Brisbane/60/2008) Hemagglutinin/HA Insect Cells Cell Lysate (WB positive control) |
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MBS8115775-03mg | MyBiosource | 0.3mg | EUR 280 |
Influenza virus B (B/Brisbane/60/2008) Hemagglutinin/HA Insect Cells Cell Lysate (WB positive control) |
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MBS8115775-5x03mg | MyBiosource | 5x0.3mg | EUR 1205 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin Antibody Pair Set |
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ABPR-ZB267 | Creative Diagnostics | 5 plates, 15 plates | Ask for price |
Description: Quantitative determination of Influenza Hemagglutinin |
H1N1 Influenza A- Virus Brisbane 59/2007 Recombinant |
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rAP-5423 | Angio Proteomie | Inquiry | Ask for price |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA ELISA Pair Set |
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MBS8118343-15Plates | MyBiosource | 15Plates | EUR 800 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA ELISA Pair Set |
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MBS8118343-5Plates | MyBiosource | 5Plates | EUR 450 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA ELISA Pair Set |
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MBS8118343-5x15Plates | MyBiosource | 5x15Plates | EUR 3695 |
Influenza A H3N2 (A/Brisbane/10/2007) HA Protein (HA1 Subunit), His Tag |
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E40VAG022 | EnoGene | 20ug | EUR 495 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (AP) |
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MBS6481610-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (AP) |
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MBS6481610-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (PE) |
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MBS6481620-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (PE) |
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MBS6481620-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A H1N1 (A/Brisbane/59/2007) HA protein, His Tag |
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E40VAG011 | EnoGene | 20ug | EUR 495 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (APC) |
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MBS6481611-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (APC) |
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MBS6481611-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (HRP) |
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Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (HRP) |
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MBS6481614-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (FITC) |
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MBS6481613-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (FITC) |
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MBS6481613-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Mouse MAb |
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MBS8104742-002mL | MyBiosource | 0.02mL | EUR 185 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Mouse MAb |
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MBS8104742-01mL | MyBiosource | 0.1mL | EUR 365 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Mouse MAb |
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MBS8104742-5x01mL | MyBiosource | 5x0.1mL | EUR 1490 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Rabbit MAb |
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MBS8104746-002mL | MyBiosource | 0.02mL | EUR 185 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Rabbit MAb |
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MBS8104746-01mL | MyBiosource | 0.1mL | EUR 385 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Rabbit MAb |
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MBS8104746-5x01mL | MyBiosource | 5x0.1mL | EUR 1590 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Rabbit MAb |
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MBS8104747-002mL | MyBiosource | 0.02mL | EUR 185 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Rabbit MAb |
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MBS8104747-01mL | MyBiosource | 0.1mL | EUR 385 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Rabbit MAb |
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MBS8104747-5x01mL | MyBiosource | 5x0.1mL | EUR 1590 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Rabbit MAb |
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MBS8104748-002mL | MyBiosource | 0.02mL | EUR 185 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Rabbit MAb |
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MBS8104748-01mL | MyBiosource | 0.1mL | EUR 385 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody, Rabbit MAb |
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MBS8104748-5x01mL | MyBiosource | 5x0.1mL | EUR 1590 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (Biotin) |
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MBS6481612-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (Biotin) |
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MBS6481612-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007)(H1N1) Peptide |
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11-563 | ProSci | 0.05 mg | EUR 632.4 |
Description: Influenza A Hemagglutinin H1 (A/Brisbane/59/2007)(H1N1) Peptide |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007)(H1N1) Peptide |
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11-564 | ProSci | 0.05 mg | EUR 632.4 |
Description: Influenza A Hemagglutinin H1 (A/Brisbane/59/2007)(H1N1) Peptide |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody (HRP), Mouse MAb |
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MBS8104743-01mg | MyBiosource | 0.1mg | EUR 440 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody (HRP), Mouse MAb |
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MBS8104743-5x01mg | MyBiosource | 5x0.1mg | EUR 1820 |
Influenza B- Virus Brisbane 60/2008 Recombinant |
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rAP-5434 | Angio Proteomie | Inquiry | Ask for price |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 405) |
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MBS6481615-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 405) |
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MBS6481615-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 490) |
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MBS6481616-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 490) |
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MBS6481616-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 550) |
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MBS6481617-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 550) |
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MBS6481617-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 650) |
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MBS6481618-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 650) |
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MBS6481618-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 750) |
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MBS6481619-01mL | MyBiosource | 0.1mL | EUR 1090 |
Influenza A Hemagglutinin H1 (A/Brisbane/59/2007) (H1N1) (MaxLight 750) |
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MBS6481619-5x01mL | MyBiosource | 5x0.1mL | EUR 4765 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody (Biotin), Rabbit MAb |
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MBS8124089-01mg | MyBiosource | 0.1mg | EUR 470 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Antibody (Biotin), Rabbit MAb |
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MBS8124089-5x01mg | MyBiosource | 5x0.1mg | EUR 1955 |
Influenza B (B/Brisbane/60/2008) HA protein, His Tag |
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E40VAG161 | EnoGene | 20ug | EUR 495 |
Influenza B (B/Brisbane/60/2008) HA protein, His Tag |
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E40VAG163 | EnoGene | 20ug | EUR 495 |
Influenza A H1N1 (A/Brisbane/59/2007) HA Protein (HA1 Subunit), His Tag |
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E40VAG010 | EnoGene | 20ug | EUR 495 |
Recombinant Influenza A virus A/Brisbane/02/2018 (H1N1) Hemagglutinin Antigen |
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VAC-0017 | Creative BioMart | 0.5ml | EUR 2398.4 |
Description: Protein |
Molecular docking and dynamics simulations research of OmpATb identifies 4 potential novel pure product-derived anti-Mycobacterium tuberculosis compounds
The outer membrane protein A (OmpATb) of Mycobacterium tuberculosis is a virulence issue that neutralizes the host pH to impede the uptake of hydrophilic antitubercular medicine.
Figuring out pure compounds with the potential to inhibit OmpATb might permit circumvention of the porin-like actions of OmpATb. 4 potential leads comprising ZINC000003958185, ZINC000000157405, ZINC000000001392 and ZINC000034268676 had been obtained by digital screening of 6394 various pure merchandise.
Characterization of the binding interactions of the potential leads with OmpATb revealed 9 essential residues comprising ARG86, LEU110, LEU113, LEU114, ALA115, PHE142, SER145, VAL146, and PHE151. Molecular dynamics simulations additionally revealed very secure protein-lead complexes.
Most residues contributed decrease binding energies to the general molecular mechanics Poisson-Boltzmann floor space (MM-PBSA) binding free energies of the interactions between the molecules and OmpATb protein.
Induced Match Docking (IFD) of the compounds regenerated poses of the molecular docking utilizing AutoDock Vina. These molecules might be beginning templates for designing inhibitors to bypass the pore mediating actions of OmpATb.
Based mostly on structural similarity, ZINC000034268676 was urged as a possible scaffold for designing efflux pump inhibitors of the gate mediating actions of OmpATb and should improve the uptake of hydrophilic medicine to scale back the length time of tuberculosis therapy.
Moreover, structurally comparable compounds obtainable within the DrugBank database with a similarity threshold of 0.7 have been reported to exhibit antitubercular and anti-mycobacterial actions.
These biomolecules may be additional characterised experimentally to corroborate their antitubercular exercise. Additionally, the skeletons of the molecules may be adopted as sub-structures for the design of future anti-mycobacterial medicine.
Key phrases: Antitubercular compounds; Induced-fit docking; MM-PBSA; Molecular docking; Molecular dynamics; Mycobacterium tuberculosis OmpATb; Pure merchandise; Digital screening.
Probing the Molecular-Stage Interactions in an Energetic Pharmaceutical Ingredient (API) – Polymer Dispersion and the Ensuing Affect on Drug Product Formulation.
An investigation of underlying mechanisms of API-polymer interplay patterns has the potential to offer helpful insights for choosing applicable formulations with superior bodily stability and processability.
On this examine, copovidone was used as a polymeric provider for a number of mannequin compounds together with clotrimazole, nifedipine, and posaconazole.
The various chemical constructions conferred the power for the mannequin compounds to type distinct interactions with copovidone. Rheology and nuclear magnetic resonance (NMR) had been mixed to research the molecular sample and relative power of energetic pharmaceutical ingredient (API)-polymer interactions.
As well as, the affect of the interactions on formulation processability by way of sizzling soften extrusion (HME) and bodily stability had been evaluated.The rheological response of an API-polymer system was discovered to be extremely delicate to API-polymer interplay, relying each on API chemistry and API-polymer miscibility.
Within the techniques studied, dispersed API induced a stronger plasticizer impact on the polymer matrix in comparison with crystalline/aggregated API.
Correspondingly, the processing torque by way of HME confirmed a proportional relationship with the utmost advanced viscosity of the API-polymer system. To be able to quantitatively consider the relative power of the API-polymer interplay, homogeneously dispersed API-polymer amorphous samples had been ready by HME at an elevated temperature. DSC, XRD, and rheology had been employed to verify the amorphous integrity and homogeneity of the resultant extrudates.
Subsequently, the homogeneously dispersed API-polymer amorphous dispersions had been interrogated by rheology and NMR to offer a qualitative and quantitative evaluation of the character of the API-polymer interplay, each macroscopically and microscopically.
Rheological grasp curves of frequency sweeps of the extrudates exhibited a powerful dependence on the API chemistry and revealed a rank ordering of the relative power of API-copovidone interactions, within the order of posaconazole > nifedipine > clotrimazole.
NMR knowledge offered the means to exactly map the API-polymer interplay sample and determine the particular websites of interplay from a molecular perspective. Lastly, the affect of API-polymer interactions on the bodily stability of the resultant extrudates was studied.
Qualitative and quantitative analysis of the relative power of the API-polymer interplay was efficiently achieved by using mixed rheology and NMR. Graphical Summary.
Galectin-1, Human |
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MBS8575305-0005mg | MyBiosource | 0.005mg | EUR 245 |
Galectin-1, Human |
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MBS8575305-5x0005mg | MyBiosource | 5x0.005mg | EUR 940 |
Mouse anti Human Galectin-1 Antibody, Mouse MAb |
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MBS2543309-006mL | MyBiosource | 0.06mL | EUR 250 |
Mouse anti Human Galectin-1 Antibody, Mouse MAb |
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MBS2543309-012mL | MyBiosource | 0.12mL | EUR 370 |
Mouse anti Human Galectin-1 Antibody, Mouse MAb |
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MBS2543309-02mL | MyBiosource | 0.2mL | EUR 550 |
Human Galectin-1 (Gal-1) Antibody |
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30005-05111 | AssayPro | 150 ug | EUR 215 |
Human Galectin( Galectin) Elisa Kit |
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EK711568 | AFG Bioscience LLC | 96 Wells | EUR 0.18 |
RABBIT ANTI HUMAN GALECTIN-3:Biotin |
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MBS222930-005mg | MyBiosource | 0.05mg | EUR 655 |
RABBIT ANTI HUMAN GALECTIN-3:Biotin |
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MBS222930-5x005mg | MyBiosource | 5x0.05mg | EUR 2780 |
Rabbit Anti-Human Galectin-1 |
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102-PA131 | Angio Proteomie | 100ug | EUR 240 |
Anti-Human Galectin-1 Antibody |
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102-P131 | ReliaTech | 100 µg | EUR 245.7 |
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and anti-inflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity. |
Anti-Human Galectin-1 Antibody |
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102-PA131AG | ReliaTech | 50 µg | EUR 157.5 |
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity. |
Anti-Human Galectin-1 Antibody |
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102-PA131S | ReliaTech | 100 µg | EUR 126 |
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity. |
human anti-human galectin-3 mAb(2D) |
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E4A09H10-2D | EnoGene | 50ug | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(5F) |
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E4A09H10-5F | EnoGene | 50ug | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(A5) |
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E4A09H10-A5 | EnoGene | 50ug | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(G2) |
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E4A09H10-G2 | EnoGene | 50ug | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(H3) |
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E4A09H10-H3 | EnoGene | 50ug | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
human anti-human galectin-3 mAb(T1) |
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E4A09H10-T1 | EnoGene | 50ug | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Human Galectin-1 (LGALS1) |
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1-CSB-EP012882HU | Cusabio |
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Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli |
Human Galectin-1 (LGALS1) |
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1-CSB-EP012882HUb1 | Cusabio |
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Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli |
Mouse anti Human Galectin-1/LGALS1 Monoclonal Antibody |
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MBS2543310-006mL | MyBiosource | 0.06mL | EUR 250 |
Mouse anti Human Galectin-1/LGALS1 Monoclonal Antibody |
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MBS2543310-012mL | MyBiosource | 0.12mL | EUR 370 |
Mouse anti Human Galectin-1/LGALS1 Monoclonal Antibody |
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MBS2543310-02mL | MyBiosource | 0.2mL | EUR 550 |
human anti-human galectin-3 mAb(N13) |
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E4A09H10-N13 | EnoGene | 50ug | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Human Galectin-1 Protein |
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PRP1033-100g | Abbkine | 100 µg | EUR 309 |
Human Galectin-1 Protein |
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PRP1033-1mg | Abbkine | 1 mg | EUR 1099 |
Human Galectin-1 Protein |
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PRP1033-20g | Abbkine | 20 µg | EUR 79 |
Rabbit anti Human Galectin-1/LGALS1 Monoclonal Antibody |
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MBS2543912-006mL | MyBiosource | 0.06mL | EUR 250 |
Rabbit anti Human Galectin-1/LGALS1 Monoclonal Antibody |
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MBS2543912-012mL | MyBiosource | 0.12mL | EUR 370 |
Rabbit anti Human Galectin-1/LGALS1 Monoclonal Antibody |
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MBS2543912-02mL | MyBiosource | 0.2mL | EUR 550 |
Rabbit anti Human Galectin-1/LGALS1 Monoclonal Antibody |
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MBS2543913-006mL | MyBiosource | 0.06mL | EUR 250 |
Rabbit anti Human Galectin-1/LGALS1 Monoclonal Antibody |
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MBS2543913-012mL | MyBiosource | 0.12mL | EUR 370 |
Rabbit anti Human Galectin-1/LGALS1 Monoclonal Antibody |
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MBS2543913-02mL | MyBiosource | 0.2mL | EUR 550 |
Anti Human Galectin-3 Polyclonal Antibody |
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KH040 | Sceti | each | EUR 778.8 |
Description: The Anti Human Galectin-3 Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur. |
Human Galectin-3(Galectin-3)ELISA Kit |
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YLA0216HU-48T | Shanghai YL Biotech | 48T | Ask for price |
Human Galectin-3(Galectin-3)ELISA Kit |
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YLA0216HU-96T | Shanghai YL Biotech | 96T | Ask for price |
Recombinant Human Galectin-1 |
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7-00427 | CHI Scientific | 10µg | Ask for price |
Recombinant Human Galectin-1 |
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7-00428 | CHI Scientific | 50µg | Ask for price |
Recombinant Human Galectin-1 |
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7-00429 | CHI Scientific | 1mg | Ask for price |
Recombinant Human Galectin-1 |
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AP60482 | SAB | 100ug | EUR 449 |
Recombinant Human Galectin-1 |
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HEOPP-0710 | Cyagen | 10ug | Ask for price |
RECOMBINANT HUMAN GALECTIN-1 |
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GWB-BEA2B0 | GenWay Biotech | 0.05 mg | Ask for price |
Recombinant Human Galectin-1 |
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cyt-544-10g | ProSpec Tany | 10µg | EUR 60 |
Recombinant Human Galectin-1 |
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cyt-544-1mg | ProSpec Tany | 1mg | EUR 1350 |
Recombinant Human Galectin-1 |
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cyt-544-50g | ProSpec Tany | 50µg | EUR 145 |
Recombinant Human Galectin-1 |
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MBS143303-001mg | MyBiosource | 0.01mg | EUR 240 |
Recombinant Human Galectin-1 |
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MBS143303-005mg | MyBiosource | 0.05mg | EUR 310 |
Recombinant Human Galectin-1 |
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MBS143303-1mg | MyBiosource | 1mg | EUR 1515 |
Recombinant Human Galectin-1 |
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MBS143303-5x1mg | MyBiosource | 5x1mg | EUR 6485 |
RECOMBINANT HUMAN GALECTIN-1 |
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MBS232407-005mg | MyBiosource | 0.05mg | EUR 500 |
RECOMBINANT HUMAN GALECTIN-1 |
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MBS232407-5x005mg | MyBiosource | 5x0.05mg | EUR 2070 |
Recombinant Human Galectin-1 |
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P1229-.01 | ApexBio | 10ug | EUR 108.8 |
Description: Peptides & Proteins|Recombinant Proteins |
Recombinant Human Galectin-1 |
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P1229-.1 | ApexBio | 10X10ug | EUR 450.4 |
Description: Peptides & Proteins|Recombinant Proteins |
Recombinant Human Galectin-1 |
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P1229-.5 | ApexBio | 50X10ug | EUR 1010.4 |
Description: Peptides & Proteins|Recombinant Proteins |
Recombinant Human Galectin-1 |
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MBS9420409-002mg | MyBiosource | 0.02mg | EUR 285 |
Recombinant Human Galectin-1 |
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MBS9420409-01mg | MyBiosource | 0.1mg | EUR 470 |
Recombinant Human Galectin-1 |
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MBS9420409-1mg | MyBiosource | 1mg | EUR 1785 |
Recombinant Human Galectin-1 |
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MBS9420409-5x1mg | MyBiosource | 5x1mg | EUR 7885 |
Recombinant Human Galectin-1 |
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MBS966052-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 255 |
Recombinant Human Galectin-1 |
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MBS966052-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 405 |
Recombinant Human Galectin-1 |
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MBS966052-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 1425 |
Recombinant Human Galectin-1 |
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MBS966052-5x1mgEColi | MyBiosource | 5x1mg(E-Coli) | EUR 6215 |
anti- Galectin-1 antibody |
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FNab03314 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against Galectin-1 |
anti- Galectin-1 antibody |
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FNab03315 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against Galectin-1 |
Anti- Galectin-1 Antibody |
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GWB-6F6392 | GenWay Biotech | 0.1 mg | Ask for price |
Human Galectin 1 Protein |
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20-abx066725 | Abbexa |
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Human Galectin-1 Antibody Pair Set |
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ABPR-ZB244 | Creative Diagnostics | 5 plates, 15 plates | Ask for price |
Description: Quantitative determination of Human Galectin-1 |
Galectin-1, human recombinant |
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4648-10 | Biovision | each | EUR 170.4 |
Galectin-1, human recombinant |
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4648-1000 | Biovision | each | EUR 1977.6 |
Galectin-1, human recombinant |
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4648-50 | Biovision | each | EUR 314.4 |
Galectin-1 Human Recombinant |
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rAP-2252 | Angio Proteomie | Inquiry | Ask for price |
Galectin-1 (human), (recombinant) |
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MBS567229-01mg | MyBiosource | 0.1mg | EUR 750 |
Galectin-1 (human), (recombinant) |
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MBS567229-5x01mg | MyBiosource | 5x0.1mg | EUR 3320 |
Anti-Human Galectin-1 Azide Free |
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MBS335796-02mg | MyBiosource | 0.2mg | EUR 290 |
Anti-Human Galectin-1 Azide Free |
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MBS335796-05mg | MyBiosource | 0.5mg | EUR 555 |
Anti-Human Galectin-1 Azide Free |
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MBS335796-5x05mg | MyBiosource | 5x0.5mg | EUR 2465 |
Anti-Human Galectin-1 Azide Free |
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MBS335797-02mg | MyBiosource | 0.2mg | EUR 290 |
Anti-Human Galectin-1 Azide Free |
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MBS335797-05mg | MyBiosource | 0.5mg | EUR 555 |
Anti-Human Galectin-1 Azide Free |
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MBS335797-5x05mg | MyBiosource | 5x0.5mg | EUR 2465 |
Human Galectin-1 ELISA Kit |
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EK5323 | SAB | 96 tests | EUR 599 |
Human Galectin-1 ELISA Kit |
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IHULGALS1KT | Innovative research | each | EUR 702 |
Description: Human Galectin-1 ELISA Kit |
Human Galectin-1 ELISA Kit |
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MBS765403-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3900 |
Human Galectin-1 ELISA Kit |
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MBS765403-48StripWells | MyBiosource | 48-Strip-Wells | EUR 340 |
Human Galectin-1 ELISA Kit |
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MBS765403-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2045 |
Human Galectin-1 ELISA Kit |
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MBS765403-96StripWells | MyBiosource | 96-Strip-Wells | EUR 455 |
Human Galectin-1 ELISA Kit |
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MBS8414441-1Kit | MyBiosource | 1Kit | EUR 755 |
Human Galectin-1 ELISA Kit |
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MBS8414441-5x1Kit | MyBiosource | 5x1Kit | EUR 3455 |
Human Galectin-1 ELISA Kit |
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MBS2883188-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3290 |